Patient's question:
Hello! My son is 2 years old this year, and we are preparing to send him to kindergarten. During the kindergarten entrance physical examination, the fifth item of the hepatitis B two pairs of semi quantitative test is +. What does this mean? Is it serious?Doctor's answer:
Hepatitis B virus carrier, contagious.(1) HBsAg - Hepatitis B surface antigen
(2) HBsAb - Hepatitis B surface antibody
(3) HBeAg - Hepatitis B e antigen
(4) HBeAb - Hepatitis B e antibody
(5) HBcAb - Hepatitis B core antibody. Different clinical significances are as follows:
1. (1, 3, 5) Continuous replication of hepatitis B virus, high contagiousness, commonly referred to as "three positive."
2. (2, 5) Acute or chronic hepatitis, contagious: If it results from "three positive," it suggests that viral replication is tending to stop, and contagiousness is low.
3. (1) There are four possibilities:
A. Early stage of acute infection;
B. Virus carrier;
C. Derived from "three positive," indicating that viral replication is tending to stop, and contagiousness is low;
D. The core of the virus has integrated with the core of human liver cells, and it is non-contagious.
4. (1, 4, 5) Acute phase or virus carrier, low contagiousness.
5. (2) Virus has been cleared, non-contagious, and immunity is present; immunity has been acquired after receiving the hepatitis B vaccine; also seen in false positives.
6–8. (2, 4; 4, 5; 5) Virus has been eliminated, immunity is present, and it is non-contagious.
9. (1, 3) Early stage of hepatitis B virus infection, high contagiousness.
10. (1, 4) Recovery phase of hepatitis B or chronic virus carrier.
11. (1, 3, 4, 5) Acute or chronic hepatitis, virus carrier, moderate contagiousness.
12. (1, 2) Secondary infection with different subtypes of hepatitis B virus; early stage of atypical hepatitis B virus infection; or transition period (this is rare).
13–15. (1, 2, 3, 5; 1, 2, 4, 5; 1, 2, 4) Hepatitis B virus mutation; or transition period (this is rare).
16. (3, 5) Atypical acute infection (suggests other types of hepatitis).
17–18. (2, 3; 2, 3, 5)