Patient's question:
My nephew has been born for five months, and he is a seven-month premature baby. The child was smaller than other children at birth, and feeding was difficult. He ate very little and grew very slowly. The child often cried at night, and every time he finished nursing, he would vomit milk, which felt like nausea. Taking the child to the hospital for a thorough examination, they said it was due to hepatocellular jaundice.What kind of assistance is needed: How should neonatal prolonged hepatocellular jaundice be treated?
Doctor's answer:
Cholestasis in children refers to the persistent increase in bile secretion in infants due to liver cell damage and/or obstruction of intrahepatic or extrahepatic bile ducts. Clinical diagnosis is primarily characterized by conjugated hyperbilirubinemia [i.e., direct bilirubin > 25.5 μmol/L (1.5 mg/dL) or the ratio of direct to total bilirubin > 20%], hepatosplenomegaly, abnormal liver function, and poor fat metabolism. Some refer to this condition as infantile hepatitis syndrome. Cholestasis is treatable, such as in cases of biliary atresia, choledochal cysts, or gallstones, which can be surgically treated. Bacterial, toxoplasma, or syphilis infections can be treated with antibiotics.