Evidence-Based Cardiovascular Disease. Concepts and Clinical Applications: Concepts and Clinical Applications

Author: Xu Yuyun
Publisher:
Publish Date: 2001-05-01
Features: The author concisely summarizes the main issues of evidence-based cardiovascular disease, such as drug treatment strategies for arrhythmias, advances in the treatment of chronic heart failure, and thrombolytic therapy for acute myocardial infarction. Emphasizing clinical practice, the book introduces significant progress in the prevention and treatment of cardiovascular diseases under the evidence-based medicine model and provides specific examples of its clinical application. This is a valuable book that explains the principles of evidence-based medicine from theory to practice, playing a crucial pioneering role in promoting evidence-based medicine in China.
Chapter Overview: Before the 1980s, research and medical practice in the prevention and treatment of cardiovascular diseases largely followed an experience-based and speculative medical model. Clinical surrogate markers (Clinical Surrogate) were used to evaluate the safety and effectiveness of drug or non-drug treatment methods. These surrogate markers included blood pressure, arrhythmias (such as premature ventricular contractions, atrial fibrillation, etc.), hemodynamics, and blood biochemical indicators (such as blood glucose and blood lipids). Although this model could temporarily improve patients' symptoms, it overlooked prognostic indicators.