Patient's question:
Little girl as soon as she eats hot-natured (referring to fried foods) or has a fever, it triggers bronchial asthma. It's already the fourth time this year. I'd like to understand what good methods there are to prevent it from recurring, and how to get rid of it once and for all...Doctor's answer:
Medications for asthma are often referred to as bronchodilators because they all possess the effect of bronchodilation.1. Beta-2 agonists: Beta-2 agonists primarily work by stimulating β2-receptors in the airway smooth muscle, activating adenylyl cyclase, increasing intracellular cyclic AMP (cAMP) levels, and enhancing free Ca2+ levels, thereby relaxing the urethral smooth muscle. They are essential medications for suppressing acute asthma symptoms.
2. Theophylline: Theophylline not only inhibit phosphodiesterase to reduce intracellular cAMP levels but also possess antagonistic effects on adenosine receptors; they can also enhance the excretion of epinephrine in the body, improve the ciliary clearance function of the airways, and have anti-inflammatory effects. They are currently one of the commonly used medications for treating asthma. The varieties of drugs used in clinical diagnosis include aminophylline, theophylline, propyphenolamine, dipropylamine, enprofylline, etc. They can be taken orally or administered intravenously.
3. Anticholinergic drugs: Inhaled anticholinergic drugs, such as ipratropine bromide, can block postganglionic vagal pathways, reduce vagal excitability to produce bronchodilation, and also block reflexive urethral contraction.
Corticosteroids: Corticosteroids (full name: hormones) are currently the most effective medications for the comprehensive prevention and treatment of asthma.
Sodium cromoglicate: Sodium cromoglicate is a non-steroidal anti-inflammatory drug.
Lifestyle management: Avoiding triggers: When managing acute asthma attacks, it is important to identify the triggers. Most are related to exposure to allergens, fever, respiratory infections, changes in weather, inappropriate medication use (e.g., analgesics, β-blockers), intense exercise, or inadequate treatment. Identifying and suppressing triggers can help control the condition and prevent recurrence.