Patient's question:
Daughter. 8 years old. Coughs and wheezes during the day.Doctor's answer:
Subcutaneous injection of allergen extracts is a traditional desensitization treatment, with the dose gradually increasing from low to high concentrations to reach the maximum tolerated dose in patients and maintain the injections for three years. Since the allergenicity of dust mite is 1-2 times stronger than that of other allergens, the dosage used for dust mite desensitization treatment is generally lower. Clinically, the concentration is often diluted to 10?? to 10?1? based on the severity of dust mite allergy. The injection typically starts with 0.1 ml, administered twice a week, with the dose increased by 0.1 ml each time. After reaching 1 ml, the concentration is increased, and the injection also starts with 0.1 ml, administered twice a week, with the dose increased by 0.1 ml each time until reaching 1 ml. This process is repeated to gradually increase the concentration, with each concentration starting from 0.1 ml and increasing to 1 ml. This phase of immunotherapy is called the escalation phase, after which the maintenance phase begins. The maintenance concentration is 10?2, administered twice a week, with each maintenance dose being 0.5 ml. This should be maintained for 2-3 years. After entering the maintenance phase and symptoms stabilize, the injection dose remains unchanged, but the interval between injections can gradually be extended to once a week, then every two weeks, then monthly, until the medication is discontinued.