Patient's question:
I previously had one miscarriage with my husband, and recently I'm trying to conceive again. However, I found out yesterday that I have a chromosomal abnormality. I'm told this could lead to a miscarriage if I do get pregnant. Online says there are several types of chromosomal abnormalities, and I want to understand which one is the most severe?Doctor's answer:
Hypothesis of the condition: Chromosomes are the carriers of genes, and chromosomal abnormalities can lead to abnormal gene expression and abnormal growth and development of the body. The pathogenesis of chromosomal aberrations is still unclear, possibly due to the failure of chromosomes to fuse again during the late stage of cell division, or the fragmentation and reconnection of chromosomes under various internal and external factors. Suggestions: Some chromosomal abnormalities are merely polymorphisms or markers of hereditary transmission across generations, and they will never cause infertility, miscarriage, or embryonic arrest.