Who is more prone to chromosomal abnormalities?

Patient's question:

Recently, a colleague told me that she had recently discovered chromosomal abnormalities and that it might lead to miscarriage. I've never heard of this before, and I want to understand what kind of people are prone to chromosomal abnormalities?

Doctor's answer:

If chromosomal abnormalities are a relatively broad concept, they specifically include many types, such as numerical abnormalities of chromosomes and structural abnormalities of chromosomes. The lethal chromosomal abnormalities are very rare in the population, while the common ones in the population are mostly non-lethal abnormalities. Numerical chromosomal abnormalities often lead to multiple system developmental abnormalities, including conditions like Down syndrome (21-trisomy), Edward syndrome (18-trisomy), and Turner syndrome, among others.

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