Patient's question:
Female, 29 years old, with a history of ectopic pregnancy. In May, she underwent a culture dish procedure at the Sixth Hospital, where a twin pregnancy at 7 weeks was confirmed to be non-viable. The villus examination revealed a partial monosomy of chromosome 8. Her husband previously had a chromosome inversion detected in chromosome 7. The doctor is wondering if this is a coincidence or if it is due to an issue with her husband. For the future, should she focus solely on culture dishes (excluding embryos) or pursue some form of treatment? After a D&C one month ago, what should she pay attention to for postoperative recovery and how should she care for herself?Doctor's answer:
If it is a chromosomal inversion, it can interfere with pregnancy, possibly leading to natural delivery, embryonic arrest, and miscarriage. It may also result in chromosomal abnormalities in embryos during IVF. It is not that there may be no normal embryos; there should be, but some embryos have chromosomal abnormalities. If you want to eliminate embryos with abnormal chromosomes, it is recommended that you use a third-generation culture dish for selection. After the embryonic arrest and D&C surgery, pay more attention to rest and hygiene.