Patient's question:
Female, after undergoing the triple screen test and a thorough examination, the test report indicates a high risk. Is it possible that the fetus has a chromosomal abnormality?Doctor's answer:
It is recommended to undergo non-invasive DNA testing or amniocentesis. The accuracy rate of non-invasive DNA testing is 99%, but it only screens for three pairs of chromosomes (trisomy 13, trisomy 18, and trisomy 21). If you want to be fully tested for all 23 pairs of chromosomes, amniocentesis is the only option. The accuracy rate of amniocentesis reaches 100%, making it the gold standard for definitive diagnosis. However, amniocentesis carries a small risk of miscarriage, but this risk is less than 3%. If you are very concerned about the risk of miscarriage, you may choose non-invasive DNA testing. If there are still issues with non-invasive DNA testing, the next step would be amniocentesis.