What are the consequences of having a child with chromosomal abnormalities through test tube baby?

Patient's question:

Doctor, I have conceived a child, but it is a Down syndrome baby. I heard that in our case, IVF can prevent this. I wonder if there is a high chance of giving birth to a child with chromosomal abnormalities in a petri dish?

Doctor's answer:

For both husband and wife, whether the two pairs of chromosomes reappear abnormally (deletions, translocations, inversions, etc.), it indicates the risk of encountering generational genetic defects. Chromosomal abnormalities are also one of the important reasons for infertility in men and women. Whether undergoing the first, second, or third-generation IVF, the chance of giving birth to a child with chromosomal abnormalities is relatively low. This is because both partners have undergone thorough chromosomal testing before the procedure, especially for third-generation IVF, which is specifically designed to address chromosomal abnormalities. Before embryo transfer, comprehensive chromosomal screening of the embryos is also performed, making the probability of chromosomal abnormalities very low.

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