Patient's question:
What is the pathogenesis of interstitial nephritis?Doctor's answer:
Interstitial nephritis is caused by various etiologies that lead to damage to the renal interstitium, which can result in renal insufficiency. Its pathogenesis can be divided into drug-induced interstitial nephritis, which is the most common type, as well as infectious, physical-chemical factors, urinary tract obstruction, and some autoimmune diseases, all of which can cause interstitial nephritis. Patients with interstitial nephritis may develop edema in the renal interstitium, accompanied by inflammation cell infiltration.