Patient's question:
Recently, I've been feeling very tired and also have pain in my lower right abdomen. Sometimes, there are blood in my urine. I went to the hospital for a thorough examination and was told that I have nephrotic syndrome. I'd like to understand the symptoms of nephrotic syndrome in more detail. What are the clinical manifestations of nephrotic syndrome?Doctor's answer:
The early symptoms of your nephrotic syndrome are:1. Low protein plasma protein, a large amount of albumin is lost in the urine, increasing the compensatory production of albumin in the liver. When the enhanced production of liver albumin is insufficient to eliminate the loss, the early symptoms of low albumin nephrotic syndrome reappear.
2. Edema is also a common symptom of nephrotic syndrome. Low albuminemia increases the colloid osmotic pressure of plasma, causing water to move from the vascular lumen into the interstitial space, which is the main reason for edema. Edema is most commonly observed in the lower limbs.