Patient's question:
When my younger brother was very young, he started not growing properly. After many years, I learned that it was dwarfism. Recently, I wanted to explain to him about a girlfriend. Based on the attitude of taking full responsibility for both parties, I would like to consult: does dwarfism be inherited over generations? Is there any way to prevent it from being inherited over generations?Doctor's answer:
Dwarfism is a genetic disease. It is a single-gene disorder located on an autosomal chromosome. The inheritance pattern is autosomal dominant, skipping generations. This has nothing to do with gender, so the incidence of dwarfism is the same in boys and girls. The main manifestations are achondroplasia and dysplasia. Due to the single-gene dominant inheritance pattern, as long as one defective gene can be passed down through generations, because the probability of an affected parent passing the disease to their children is 50%.