Patient's question:
I have been married to my wife for several years, and we haven't had any children yet. Recently, we had a thorough check-up and found that I have abnormal chromosomes. Can people with chromosomal abnormalities undergo in vitro fertilization?Doctor's answer:
Patients with chromosomal abnormalities who conceive naturally may pass on abnormal chromosomes across generations, leading to miscarriage,malformations, or hereditary defects in the fetus. It is recommended to undergo third-party IVF. Third-party IVF, also known as preimplantation genetic diagnosis (PGD), involves molecular genetic testing at the gamete or embryo stage to identify disease-free embryos, which are then transferred to the uterus to prevent early pregnancy with genetic disorders. Third-party IVF confirms the genetic status of the implanted embryos, effectively preventing selective miscarriage and addressing associated ethical concerns. This is a blessing for patients with chromosomal abnormalities. However, this technology is only available in major perinatal centers.