Patient's question:
When performing hepatitis B virus resistance testing, what should be noted? I am a hepatitis B patient, and I have been taking medication for almost a year. Recently, I feel that the effect of the medication is not very good. I have also started to feel uncomfortable. I suspect that it has resistance to the hepatitis B virus. So, what should be noted when performing hepatitis B virus resistance testing?Doctor's answer:
HBVDNA testing provides reliable evidence for clinical diagnosis and regulation, becoming an important basis for analyzing the efficacy of clinical treatment. If the test is positive and the viral load is high, active treatment is necessary, otherwise the condition may worsen. Some individuals may experience repeated fluctuations in their condition, leading to liver cirrhosis; others may develop cancer due to the integration of HBV DNA and human liver cell DNA. Clinical research has shown that the hepatitis B virus itself is highly variable. During the treatment of chronic hepatitis B, HBVDNA testing can detect whether drug resistance has developed in the patient, which is beneficial for guiding clinical treatment and more quickly reversing the condition.