What factors trigger asthma?

Patient's question:

The other day, while taking a nap, I suddenly experienced difficulty breathing and coughing. On the third day, I went to the hospital for a thorough examination, and the result was asthma. How did the asthma come about?

Doctor's answer:

Asthma is a chronic inflammatory disease of the airways that is mediated by various inflammatory cells such as mast cells, eosinophils, and lymphocytes. Due to the high reactivity of the airways to multiple different influencing factors, reversible airflow limitation may occur, leading to severe chest pain or constriction, which can trigger asthma attacks. Asthma has a polygenic hereditary pattern and is genetically predisposed, potentially associated with autoimmune inflammatory mechanisms. Both congenital hereditary factors and postnatal environmental factors play important roles in the onset of this disease. In the treatment of asthma, inhaled corticosteroids or drugs that inhibit leukotriene release are generally used.

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