What are the reasons for hemolytic reactions during blood transfusion?

Patient's question:

Because it was found that there is leukemia through careful examination, it is recommended to have surgery for treatment. It is said that during the surgical treatment, there may be a transfusion reaction again, the most severe being a reoccurrence of hemolytic reaction. What symptoms would the patient have if they experience a hemolytic reaction again during the surgery?

Doctor's answer:

Hemolytic reaction refers to the destruction of red blood cells in the blood, which can lead to symptoms such as headache and chest pain, with significant impact. There are many causes of hemolytic reactions, such as healthcare providers administering incompatible blood to recipients, transfusing spoiled blood, Rh incompatibility, and more. These factors can all cause hemolytic reactions, so healthcare providers need to conduct thorough pre-transfusion checks and avoid using spoiled blood.

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