Patient's question:
10 years of onset, now 18 years of course, can walk on flat ground, but cannot go up and down stairs. Except for no strength in limbs and waist, no other symptoms. No family medical history. Have a younger brother and sister, both of whom are healthy. How is it possible to get married and have children in this condition? Do you have any cases of limb-girdle muscular dystrophy?Doctor's answer:
Duchenne muscular dystrophy is a group of primary skeletal muscle necrotic diseases characterized by progressive skeletal muscle weakness, caused by familial intergenerational genetic factors. Clinically, it primarily manifests as progressive muscle enlargement and weakness of varying degrees and arrangements, accompanied by fatigue and cardiomyopathy. The cause of muscular dystrophy is abnormal familial genetic mutations, so there is currently no specific treatment for self-recovery. Additionally, there is a high probability of inheriting this condition to the next generation through familial intergenerational transmission, and the risk is even higher with consanguineous marriages.