Patient's question:
Your good friends both have mild thalassemia and are of the same type. Their first child has been carefully checked and confirmed to have severe thalassemia, so they didn't keep it. Can your good friends' second child be kept?Hello, why do both of your friends have a?
Doctor's answer:
If both partners are carriers of thalassemia minor, there is a 1/4 chance that their next child will be normal, a 1/2 chance that the child will be a carrier of thalassemia minor, and a 1/4 chance that the child will have moderate to severe thalassemia. It is recommended to undergo amniocentesis around the mid-pregnancy period, approximately 17-14 days, to obtain fetal tissue cells for genetic testing. This will confirm the presence of thalassemia major and help understand the genetic defects and mutations.