What are the clinical manifestations of pyelonephritis?

Patient's question:

Recently, my appetite hasn't been very good. Sometimes, even after eating a small amount of food, I feel a sense of fullness and indigestion in my abdomen. Seeing greasy food even makes me feel nauseous and vomit. My body is also particularly weak and easily fatigued, and I've also lost some weight. After a careful examination at the hospital, they said it was pyelonephritis. I'm very worried now.
What kind of help do you need: Does pyelonephritis have any complications?

Doctor's answer:

Glomerulonephritis primarily manifests with symptoms such as proteinuria, hematuria, edema, and hypertension. Due to the high concealment of kidney diseases, the early symptoms of glomerulonephritis are often not apparent and may be easily overlooked. Clinical surveys indicate that patients with glomerulonephritis often miss the best opportunity for treatment, leading to the gradual progression of kidney fibrosis, ultimately resulting in kidney failure and uremia, where conventional dialysis or kidney transplantation is required to sustain life.
The treatment of infected foci in glomerulonephritis currently advocates for the active use of antibiotics when bacterial culture of the focus is positive. Commonly used antibiotics include penicillin or macrolides to suppress the infected focus. This approach helps prevent the spread of bacteria and typically lasts for about 2 weeks or until natural recovery.

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