Patient's question:
I am 53 years old. Recently, as I have gotten older, I have been experiencing leg pain. I have previously visited the immunology department, but the effect was not significant. I have taken both Chinese and Western medicine, especially when the weather changes, I feel uncomfortable. Can systemic lupus erythematosus be inherited?Doctor's answer:
The disease of lupus has a certain genetic component, but it is not an inherited disease, and not all descendants will inherit it. Additionally, women are more likely to develop the disease than men. Lupus is an autoimmune disease that affects multiple systems and organs, characterized by the presence of various autoantibodies. Its onset is closely related to genetic factors, so systemic lupus has a certain degree of heritability. Systemic lupus is associated with HLA-DR2, and it is a polygenic and polylocus genetic condition. It is not a 100% dominant inheritance, but individuals with systemic lupus have a slightly higher chance of developing the disease compared to the general population.