Basic Issues in Modern Pathology Clinical Research - For Use by Medical Graduate Students and Undergraduate Students of Pathology

Author: Chen Li
Publisher:
Publish Date: 2007-01-01
Features: This book primarily introduces the trends in the forefront development of pathology, new discoveries in pathological changes of diseases, methods of genetic diagnosis, and the latest achievements and dynamics in pathological research. The book consists of thirty-eight chapters, systematically elaborating on fundamental aspects of molecular pathology such as apoptosis, adhesion molecules, regulation of the cell cycle, the impact of telomerase on cellular biological behavior, and signal transduction pathways. It places special emphasis on oncology research, including tumor angiogenesis, mechanisms of tumor invasion and metastasis, fundamental theories of tumor formation, strategies for gene therapy of tumors, the significance of glycan structures of glycoproteins in tumor research, as well as the WHO pathological classification and TNM staging of common tumors such as lung cancer, gastric cancer, liver cancer, breast cancer, cervical cancer, thyroid cancer, prostate cancer, lymphoma, and glioma, along with corresponding research progress. The book also provides reviews on special events in clinical and pathological research, such as the differentiation of benign and malignant lymph node hyperplasia, the understanding of borderline lesions in the breast, and gastrointestinal stromal tumors (GIST). Additionally, it addresses public health concerns such as AIDS, environmental diseases, and aging and anti-aging research progress. The book also incorporates advancements in high-tech developments and new technologies applied in pathology, such as methods for tumor drug sensitivity testing, nanotechnology, immunohistochemistry, molecular biology techniques, electron microscopy, and ultrastructural pathology. It also discusses the relationship between pathology and clinical medicine, as well as the relationship between ethics and scientific development. The book highlights the foundational and bridging role of pathology in medical education, scientific research, and clinical practice, striving to reflect the latest developments and track the forefront of the discipline. Each topic includes systematic discussions, new developments, clinical applications, and future prospects, with chapter content arranged to be both independent and progressive, linking theory with practice. This book is suitable for medical graduate students, undergraduate students of pathology, pathologists, and clinical physicians seeking learning and improvement.