Patient's question:
I am a female carrier of hepatitis B with a high viral load (HBeAg positive). Can it be inherited to the fetus across generations? How significant is the impact on the fetus?Doctor's answer:
There are three routes of hepatitis B transmission: blood transmission, sexual transmission, and mother-to-child horizontal transmission. Since you have chronic hepatitis B (), there is a risk of directly transmitting the virus to the fetus through mother-to-child horizontal transmission. In clinical diagnosis, most prevention strategies involve combined intervention to prevent mother-to-child horizontal transmission. Generally, during the 7th, 8th, and 9th months of pregnancy, the mother receives an injection of high-titer hepatitis B immune globulin. After the baby is born, another injection is given within 6 hours, followed by a hepatitis B vaccine within 24 hours. Subsequently, additional injections are administered at one month and six months, resulting in a high transmission interruption rate. It is recommended that you consult with a local maternal and child health institution for detailed advice.