Can a small triangle of hepatitis B still turn negative?

Patient's question:

My husband was diagnosed with hepatitis B during a company health check-up, specifically the lesser hepatitis B (HBeAg negative). No wonder she has been having poor appetite and occasional nausea lately, and her hands and feet are a bit yellow. He hasn't been treated yet, but others say it's okay not to treat it, as it could still turn negative. Can the lesser hepatitis B still turn negative?

Doctor's answer:

The term "small three positive" refers to the immunological indicators of the hepatitis B virus in chronic hepatitis B patients or hepatitis B virus carriers: that is, the three are positive for hepatitis B surface antigen, hepatitis B e antibody, and hepatitis B core antibody. Some people often believe that "big three positive" is more serious while "small three positive" is harmless, which is actually a common misconception. The harm of the virus being positive in "small three positive" is increasingly being recognized by professional medical practitioners in liver diseases. Therefore, when patients face the problem of hepatitis B, we should actively adopt treatment measures and not avoid seeking medical attention. If hepatitis B is not cured after prolonged treatment, it is necessary to change the treatment plan in a timely manner.

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