First dose of hepatitis B vaccine is 20 micrograms, second dose is 10 micrograms

Patient's question:

I received the second dose of the hepatitis B vaccine at 20 micrograms, but the third dose was 10 micrograms. Is this okay? Will it be ineffective?

Doctor's answer:

The currently used hepatitis B vaccine has a dosage of 5UG per dose for infants/children and 10UG per dose for adults. However, most scholars believe that the hepatitis B vaccine injection dosage can be increased to 10UG per dose for infants and 20UG per dose for adults. The third dose of 10 micrograms is a traditional dosage and is also acceptable. It is recommended to wait 6 to 12 months after the second dose of vaccination before administering the vaccine. If the antibody concentration is measured to be higher than 10mIU/ml, the vaccine should be administered. Hepatitis B is a disease that is not easily recoverable. Patients should always maintain an optimistic attitude and face it with a positive mindset. Only in this way can they boost their confidence in combating hepatitis B and believe that they will surely recover.

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