What is the difference between chronic nephritis and uremia?

Patient's question:

I took my dad to the hospital a few days ago for a thorough examination. After the examination results came out, it was said that he had chronic nephritis. The doctor recommended starting treatment as soon as possible. Later, he also mentioned that it might progress to uremia. What are the differences between these two conditions?

Doctor's answer:

Chronic kidney failure refers to a clinical diagnosis syndrome formed by a series of symptoms and metabolic disorders caused by various kidney diseases leading to irreversible decline in renal function. Uremia is the terminal stage of chronic kidney failure. In the uremic stage, metabolic acidosis and water and electrolyte imbalance are most common, such as recurrent significant anorexia, nausea, weakness, deep breathing, subcutaneous edema, pleural effusion, hypertension, acidosis, hyperkalemia, anemia, delirium, convulsions, hallucinations, coma, and abnormal mental states, among a series of manifestations. Urinalysis, renal function tests, and blood tests need to be performed to confirm the diagnosis.

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