Patient's question:
I have had hepatitis B for 20 years. Initially, it was the "big three positive" (HBsAg, HBeAg, anti-HBc), but after more than a year of treatment, it transformed into the "small three positive." Over the years, I have been treated in many specialized clinics and taken many medications, but I have taken fewer medications recently. On April 20 of this year, I finally had the hepatitis B five-item test and liver function test. The results are as follows: HBsAg positive, HBeAg positive, anti-HBc positive, still the "small three positive." Bilirubin 13.5, direct bilirubin 3.8, indirect bilirubin 9.7, alanine aminotransferase (ALT) 18, aspartate aminotransferase (AST) 21, gamma-glutamyl transferase (GGT) 11, alkaline phosphatase (ALP) 50, total protein 70.6, globulin 23.4, albumin 47.2, serum monoamine oxidase activity measured at 9.9, serum total bile acid measured at 1.7, and transaminase ratio 0.86.Doctor's answer:
You have a history of hepatitis B for over ten years, and currently, your condition has improved from hepatitis B with a large amount of positive surface antigen (HBeAg positive) to a small amount of positive surface antigen (HBeAg negative). This indicates a relatively good recovery. However, the hepatitis B virus still exists in your body, which can cause liver damage. Long-term medication not only increases liver pressure but also leads to viral resistance and mutation. It is recommended that you first undergo hepatitis B virus mutation and drug resistance monitoring to determine the appropriate medication to suppress the virus. You can directly click to initiate online communication with me for detailed guidance on your condition.In addition to treating liver disease, it is advised that patients pay attention to their diet in daily life and maintain a cheerful mood to enhance their physical condition and slow down the recovery process.