Patient's question:
One and a half years ago, I was diagnosed with hepatitis B with a positive result for the "big three" (HBsAg, HBeAg, and anti-HBs). I have been taking Weizhi capsules for treatment ever since. During this period, I have undergone regular check-ups. However, the recent test results show a significant improvement, with decreased transaminase levels and a reduction in viral copies. I am currently feeling very troubled.Doctor's answer:
The patient is a middle-aged male with a history of hepatitis B (). He has been taking ADV for nearly two years and recent tests revealed a viral rebound. Currently, there are mainly four types of antiviral drugs used in China. ADV has one moderate-strength antiviral drug, which is more effective for patients with viral loads of 10^4 to 10^5. When patients are on antiviral therapy, we recommend that they have regular liver function and viral tests. This is because LAM, ADV, and even ETV all have a certain possibility of viral mutation. The main clinical manifestations are viral rebound and abnormal liver function. If this situation occurs again, it is essential to go to a regular hospital for follow-up, to determine the cause of the mutation—is it due to viral mutation or non-compliance with medication.