Patient's question:
Doctor, the results from my local hospital showed that 2 items were abnormal: Alanine aminotransferase (ALT); 58 U/L, Aspartate aminotransferase (AST); 53 U/L. Is my liver serious? What consequences could develop if this progresses? Additionally, I am taking medication to treat high uric acid. Is this related to taking the medication for high uric acid?Doctor's answer:
The goal of effective treatment is: ① suppress viral replication and completely eliminate the virus; ② reduce symptoms; ③ reduce inflammation and stabilize liver function; ④ prevent the progression to liver cirrhosis and hepatocellular carcinoma; ⑤ improve the patient's survival rate. Currently, there are many methods for treating chronic hepatitis B, including antiviral drugs, immunomodulation, cytokines, antifibrosis, antisense oligonucleotides, ribozymes, etc. Effective treatment is defined as the persistent and complete clearance of HBV DNA from the blood using non-PCR technology, the conversion of HBeAg to negative with the reappearance of anti-HBe, and the reduction of ALT levels to normal. When the infection transitions from the replication phase to the integration phase, the usual outcome is resolution rather than spontaneous recovery.