Patient's question:
Detailed medical condition and consultation purpose: Doctor: Hello, my test report shows: Liquefaction time: Non-liquefiable Volume: 2 Color: Grey-white PH: 7.5 Sperm density: 80 Motility rate: 75 B: 40 C: 35 D: 25 What kind of illness does this belong to? How should it be treated?Doctor's answer:
Hello, normal semen is in a liquid state when expelled but immediately solidifies into a gel-like or clotted state. It liquefies into a watery liquid within about 10 to 20 minutes. This process is called semen liquefaction and is a normal physiological phenomenon. If semen remains in a gel-like state for more than 30 minutes after ejaculation, it is considered a pathological condition known as semen non-liquefaction.The initial liquid state of semen facilitates ejaculation, while its transformation into a gel-like state helps it remain in the female vagina without easily flowing out. Subsequently, liquefaction allows the sperm in the semen to move freely, enabling them to swim along the female reproductive tract toward the fallopian tubes, which facilitates fertilization and egg binding.
The gel-like consistency of semen is caused by coagulating proteins secreted by the seminal vesicles. On the other hand, proteolytic enzymes and fibrinolysin secreted by the prostate can break down these coagulating proteins, promoting semen liquefaction. Therefore, semen non-liquefaction is caused by an excess of coagulating proteins or a deficiency of proteolytic enzymes and fibrinolysin. During semen analysis, if the semen does not coagulate, it may be due to defects in the ejaculatory ducts or congenital absence of the seminal vesicles.
Under a microscope, non-liquefied semen shows sperm clumped together, unable to move or only slowly twitching. Such semen severely hinders sperm movement within the female reproductive tract, preventing them from ascending into the cervical canal, uterine cavity, or fallopian tubes to encounter an egg. As a result, it cannot lead to pregnancy in the female.
Common causes of semen non-liquefaction include seminal vesiculitis and prostatitis, leading to