Patient's question:
Previously, there were 2 cases of miscarriage. A thorough examination revealed abnormal translocations or inversions in the female's chromosomes. What should be done for future conception? Can they still try early pregnancy, or should they consider IVF using someone else's eggs?Doctor's answer:
It is recommended that the third-generation IVF, also known as preimplantation genetic diagnosis (PGD), be performed before embryo implantation. This involves diagnosing the hereditary disease before the embryo is transferred to the uterus, ensuring that only embryos without genetic diseases are implanted, thereby guaranteeing the normal development of early pregnancy embryos and preventing the birth of children with genetic diseases. PGD is mainly applicable to individuals with genetic diseases related to genes, chromosomal abnormalities, and high-risk populations who may be at risk of conceiving children with such conditions. Chromosomal abnormalities pose significant harm to children, so it is advisable for parents to take their child to a specialized clinic for follow-up treatment under the guidance of a doctor. In daily life, children can receive sufficient care and attention, with special attention given to their dietary needs, hoping that they can recover as soon as possible!