Patient's question:
Newborn, less than a month old, diagnosed with Down syndrome after examination. What should be done?Doctor's answer:
According to the karyotype, it can be divided into three types. Among them, the standard type and translocation type are difficult to distinguish in clinical diagnosis. The clinical manifestations of the mosaic type vary greatly depending on the proportion of normal cells, ranging from normal to typical manifestations with increasing age. The intelligence decline becomes gradually more apparent, and motor, growth, and sexual development are delayed. Approximately 30% of the children have congenital heart disease or other malformations. Due to immune dysfunction, they are prone to various infections, and the incidence of leukemia increases 10 to 30 times. If they live to adulthood, they often experience symptoms of senile dementia again after the age of 30.