Patient's question:
Does intellectual disability be inherited across generations, and what is the probability? My grandmother and uncle both have intellectual disabilities. My father has mild intellectual disability, while my mother, myself, and my husband are all normal. I want to consult about the possibility of intellectual disability being inherited across generations after I get pregnant. I want to consult about the possibility of intellectual disability being inherited across generations after I get pregnant.Doctor's answer:
As follows:If parents have low intelligence, consanguineous marriage, or physical abnormalities, or if they suffer from certain metabolic diseases such as phenylketonuria, the paternal generation can pass on congenital intellectual defects to offspring, leading to intellectual disability in children. If one parent has low intelligence or both parents have low intelligence, the incidence of intellectual disability in their children can be as high as 77-96%. If the intellectual defect is inherited across generations, it is related to many genes, and many gene or chromosomal defects can cause this disease. However, if the mother has a defect and the father is normal, it is still possible to have normal offspring. Intellectual disability has a significant impact on children, and it is recommended that parents take their children to a specialist for follow-up treatment and seek medical guidance for treatment.