What is the critical risk of the Down syndrome screening?

Patient's question:

My good friend is pregnant, and we are all very happy for her. She told us she wants to have a Down syndrome screening because it is very popular now, but she doesn't know which critical risks are involved in the screening. So, she wants to consult here and ask for the doctor's help.

Doctor's answer:

The Down syndrome screening is mainly used to screen for chromosomal abnormalities and congenital deformities. Generally, it is performed on pregnant women around the fourth month. The's serum is extracted and then tested based on age, weight, and pregnancy duration. The risk of Down syndrome is relatively high. If the Down syndrome screening rate is high, it indicates that the child may have abnormalities. Later, it is necessary to undergo an amniocentesis for a detailed examination to confirm the diagnosis.

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