Patient's question:
Wanting to start a family and have children, but I learned that SSA positivity can lead to congenital heart block in newborns and neonatal lupus. Therefore, I am under a lot of pressure now. Pregnancy with anti-SSA positivity?Doctor's answer:
Since this antibody is related to Sj?gren's syndrome, it is named SSA. It is also named after the name of the first patient detected, Ro. It has the highest incidence in Sj?gren's syndrome but can also appear in other autoimmune rheumatic diseases. It is seen in primary Sj?gren's syndrome, rheumatoid arthritis, systemic lupus erythematosus, and other autoimmune diseases. Its target antigen, Ro/SSA, is a ribonucleoprotein closely related to four types of uridine-rich ribonucleic acids (hy1, hy3, hy4, hy5).