Genomics, Proteomics and Vaccines

Author: (Italian) Grandi, Editor-in-Chief, Ma Xiankai, et al., Translators
Publisher:
Publish Date: 2006-07-01
Features: This book is a specialized work introducing the new advances in vaccine engineering, co-authored by 35 experts. The book consists of 13 chapters, providing a detailed and systematic introduction to a new technical platform for vaccine development that integrates bioinformatics, genomics, proteomics, and related technologies. It demonstrates how this platform can develop new vaccines faster and with a higher success rate compared to traditional methods. The technologies involved include: genome sequencing and analysis, DNA microarrays, two-dimensional electrophoresis and two-dimensional chromatography, mass spectrometry, high-throughput protein expression and purification, as well as examples of rapidly screening candidate vaccines using these methods. The book also lists relevant literature and website addresses for further reference. Additionally, while discussing the development of new vaccines using genetic technology, the book elaborates on the biology and pathogenic mechanisms of several important clinical pathogens. The content is novel, rich, and highly practical, making it suitable for scientists and technicians engaged in vaccine development in the fields of drug development and bioproducts, as well as for faculty and students in relevant disciplines at research institutions and universities.