Patient's question:
What causes childhood hepatoblastoma? This has been bothering me, it's really annoying? Seeking answers from doctors, thank you so much!Doctor's answer:
The possible causes of hepatoblastoma in children are not fully understood, but the detailed pathogenesis of hepatoblastoma is generally considered to be an embryonal tumor. It may result from abnormal proliferation and differentiation of hepatocytes during embryonic development, with immature liver embryonic tissue still present in the fetus or after birth. These abnormal tissues continue to proliferate, forming masses of immature tissue, which may then transform into malignant embryonal tumors. The pathological process of malignant tumors may occur in the late fetal stage and only manifest during adulthood. Hepatoblastomas are typically solid masses, with single nodules or small lobar connections in the liver, often causing deformation or displacement of the liver lobes.