Pharmacoinformatics (with CD-ROM)

Author: Zheng Geng, Wang Fei (editors)
Publisher:
Publish Date: 2004-04-01
Features: Pharmaceutical bioinformatics is a rapidly developing emerging discipline that has flourished with the implementation and advancement of the Human Genome Project. It integrates theories and methods from multiple disciplines such as life sciences, mathematics, and computer science to organize and analyze the vast biological information generated by the project, and then applies this information to the design and development of drugs, aiming to achieve rational drug design. Pharmaceutical bioinformatics is a highly applied and practical discipline. To highlight this characteristic, this book focuses on the acquisition, analysis, and application of pharmaceutical-related biological information in drug development. The content covers an overview of bioinformatics, the foundational information technology, commonly used biological and pharmaceutical information resources, basic methods of sequence alignment and database searching, nucleotide sequence analysis methods, protein sequence analysis methods, bioinformatics software related to new drug development, computer-aided drug design, computer-aided vaccine design, biochips, and pharmacogenomics. It comprehensively elaborates on the fundamental principles, analytical methods, commonly used software, and applications of bioinformatics in various stages of drug development. This book can serve as a textbook for senior undergraduate and graduate students in pharmaceutical sciences, life sciences, and related fields, as well as a reference for drug researchers and other faculty and students in different disciplines.