Can congenital pure red cell aplasia be treated with umbilical cord blood?

Patient's question:

Can aplastic anemia be treated with umbilical cord blood? The effect is not significant. My friend said that umbilical cord blood can be used to treat it. Is that true? Asking for my friend.

Doctor's answer:

Pure red cell aplasia is a relatively rare disease in clinical practice, caused by abnormal autoimmune damage to erythroid stem cells, leading to pure red cell reduction. Cord blood stem cell transplantation is a method of transplantation that is generally not used for pure red cell aplasia. Its effectiveness is inferior to bone marrow transplantation, and it is generally not considered. If the patient's antibodies increase, additional immunosuppressants need to be added for better results. For specific treatment plan determination, it is recommended to bring complete medical records and consult in detail at the outpatient department.

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