What should I do if my child has high alkaline phosphatase?

Patient's question:

My baby has yellow hands and feet. I had liver function tests done, and only the alkaline phosphatase level was high; the rest were normal.

Doctor's answer:

Alkaline phosphatase is a monophosphatase that is widely present in human tissues and body fluids, including bones, liver, breast, intestinal mucosa, kidneys, and placenta. Your child only has elevated alkaline phosphatase, while other liver function tests are mostly normal. This is not sufficient to indicate liver damage. Alkaline phosphatase has many subtypes, and the elevated level could be from other sources of phosphatase. The specific situation requires a comprehensive analysis, and it is important to listen to the advice of your attending physician.

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