How high is the jaundice of a newborn that requires a blood transfusion?

Patient's question:

Born with jaundice, it was just a little yellow on the tip of the nose. The next day, there were many small yellow dots on the nose, like yellow rice grains. By the third day, the face turned yellow. From the fifth to the sixth day, the entire body turned yellow. How high does a baby's jaundice need to be for a blood transfusion?

Doctor's answer:

Infant jaundice is a yellow spot on the skin, sclera, and mucous membranes, also known as infant hyperbilirubinemia. Its etiology is specific and complex. Severe cases can lead to bilirubinencephalopathy (kernicterus), often resulting in death and severe sequelae. Infant jaundice is typically divided into physiological jaundice and pathological jaundice. In the neonatal period, when indirect bilirubin increases by more than 20% for any reason, it can enter the brain tissue and cause brain tissue damage and kernicterus.

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