Patient's question:
Please ask:1- How is semen considered nonliquefied in males?
2- After sexual intercourse, if the semen in the condom becomes viscous and stringy like cervical mucus during a woman's ovulation period, is it considered nonliquefied?
3- If a male's semen liquefies slowly, and the woman lies down for a longer time after intercourse, can pregnancy occur?
Doctor's answer:
Hello: Semen exists in a liquid state within the reproductive tract. When semen is ejected from the penis, it immediately transforms into a jelly-like or coagulated, milky substance. At this stage, sperm are contained within the semen or attached to its surface and cannot move freely. After 5–45 minutes, semen undergoes an automatic liquefaction process, turning the gel into a thin, flowing liquid. This aggregation-liquefaction process is enzyme-catalyzed. The seminal vesicles secrete a protein-like substance that forms the matrix for the gel-like material, while the prostate gland secretes a fibrinolytic enzyme that participates in the liquefaction process. This enzyme can also dissolve the clot. Some researchers have isolated a liquefaction factor with a molecular weight of 33,000 from semen. When the prostate or seminal vesicles are inflamed, due to a lack or destruction of proteinolytic enzyme secretion, the enzyme system becomes disrupted, leading to some patients' semen remaining unliquefied even after 1 hour or liquefying incompletely with excessive viscosity. This condition is known as semen non-liquefaction, which is a pathological phenomenon. In such cases, sperm cannot migrate, naturally resulting in infertility. Therefore, diseases of the seminal vesicles and prostate gland are significant causes of non-liquefaction.Methods for treating semen non-liquefaction include the following:
(1) Completely treating primary conditions such as prostatitis or seminal vesiculitis to restore their normal function.
(2) Using physiological saline containing 4% α-amylase to rinse the vagina before intercourse, or injecting 1 milliliter of it into the vagina after intercourse. Alternatively, 50 milligrams of this enzyme can be mixed with cocoa butter to form a 3-centimeter-long suppository, which is inserted into the vagina before intercourse. This method has been developed...