Human AIDS

Author: Zeng Qingping
Publisher:
Publishing Date: 2001-08-01
Features: This book systematically elaborates on the molecular virology and molecular immunology of AIDS. From the perspectives of the etiology, epidemiology, histopathology of AIDS, as well as the interaction between host cells and the virus, it introduces the pathogenesis of HIV and the series of molecular events involved, including the origin of HIV, systematic evolution, molecular evolution, genetic drift, antigenic mutation, gene expression and regulation, apoptosis, immune escape, cell tropism, and infection dynamics. It basically reflects the latest advances in the international AIDS research field after 1995. The book also provides a comprehensive summary of clinical laboratory tests, diagnosis, and treatment of AIDS, particularly the clinical guidelines for chemotherapy (HAART), and introduces the current status of human trials for AIDS vaccines, as well as prospects the application prospects of gene therapy and other biotherapies. The book is richly illustrated and concise, being one of the most systematic and comprehensive monographs on human AIDS in China. The listed AIDS websites in the book can be used by readers to explore further relevant information. The content of the book covers both basic research and clinical applications of AIDS, emphasizing both theory and practice, making it suitable for clinical doctors of AIDS, health prevention personnel, faculty and students of relevant majors in higher education institutions, and scientific researchers working in virology, pathology, and immunology in research institutions. Due to certain genomes being recombinants of two or more distinct lineages, such as the SIVs from the red colobus subspecies in the African green monkey genus being recombinants of viruses from the African green monkey lineage and the white-faced saki lineage, the evolutionary tree established based on this cannot represent the true evolutionary history of these viruses.