What are the reasons for semen not liquefying?

Patient's question:

I have had prostatitis before, currently married for four years without children, and my semen is jelly-like and colorless.

Doctor's answer:

Hello! The common causes of semen liquefaction failure include prostatitis and seminal vesiculitis leading to insufficient secretion of fibrinolytic enzymes by the prostate; deficiencies in trace elements (such as magnesium, zinc, etc.); congenital absence of the prostate, and so on. It is generally believed that the secretions of the prostate and seminal vesicles contribute to the coagulation and liquefaction processes of semen. The coagulation factor produced by the seminal vesicles causes semen coagulation, while the liquefaction factors such as protease and fibrinolytic enzymes produced by the prostate cause semen liquefaction. Once inflammation occurs in the seminal vesicles or prostate, it can disrupt the secretion of these factors, leading to an accumulation of coagulation factors or an increase in liquefaction factors, resulting in semen liquefaction failure.

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