What are the causes of Down syndrome?

Patient's question:

Three or four days ago, I visited my distant relatives and found that their baby had Down syndrome. It made me feel very pity, but the baby was very cute. I would like to ask, what is the cause of Down syndrome?

Doctor's answer:

21-trisomy syndrome is a congenital malformation disease caused by chromosomal structural abnormalities, and 10% of 21-trisomy syndrome is due to an extra chromosome from the father. Second, teratogenic substances in the environment, such as radiation, can cause chromosomal abnormalities. If a woman's abdomen is exposed to radiation before pregnancy or during pregnancy, the risk of having a 21-trisomy syndrome child will increase.

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