What are the symptoms of hand, foot, and mouth disease?

Patient's question:

How to prevent it? Is it contagious? Through what routes can it be transmitted? What are the symptoms of hand, foot, and mouth disease? How to prevent it? Is it contagious? Through what routes can it be transmitted?

Doctor's answer:

Most patients have mild symptoms, acute onset, fever, maculopapular and vesicular rashes on the palms or soles, and rashes on the buttocks or knees. The rash is surrounded by inflammatory erythema, with less fluid in the blisters. There are scattered vesicles on the oral mucosa with significant pain. Some children may also have symptoms such as cough, runny nose, poor appetite, nausea, vomiting, and headache. A few patients may develop complications such as aseptic meningitis, encephalitis, acute flaccid paralysis, respiratory infections, and myocarditis. Individual severely ill children may deteriorate rapidly and are prone to death. Children and adults do not develop symptoms after infection but can spread the virus. The enteroviruses that cause hand, foot, and mouth disease include certain serotypes of enterovirus 71 and group A coxsackievirus and echovirus. It is contagious, mainly through contact infection, so attention should be paid to handwashing. Typically, children under the age of 5 are affected.

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