Patient's question:
Left breast swelling and enlargement, right breast has also started to enlarge in recent days but without pain, bone age shows 8 years old, actual age 6.5 years old, female child, height 130 cm, weight 42 jin.Doctor's answer:
Precocious puberty is a common developmental abnormality of the pediatric endocrine system. It refers to the abnormal development of secondary sexual characteristics in girls before the age of 8. Central precocious puberty (CPP) occurs due to an increased secretion and release of gonadotropin-releasing hormone (GnRH) in the hypothalamus, which prematurely activates the function of the hypothalamic-pituitary-gonadal axis, leading to the development of gonads and the secretion of sex hormones. This results in the development of internal and external genitalia and sexual characteristics. CPP is also known as GnRH-dependent precocious puberty, and its progression is gradual until the reproductive system matures. GnRHa can effectively inhibit the secretion of LH, halt the development of the gonads, and suppress the release of sex hormones before puberty. This delays bone growth and integration, thereby extending the growth period and promoting growth to maximize the final adult height as much as possible.