Is topical prostaglandin cream effective?

Patient's question:

What problems might the topical cream for prostaglandin synthesis inhibitors cause for me in terms of perinatal or male aspects? I am a 22-year-old male in good condition. Today at noon, I lifted something heavy and suddenly my hand started to hurt. When I put it down, I had previously had tenosynovitis. What kind of help do you need: I would like to ask if the topical indomethacin patches (prostaglandin synthesis inhibitors) will have any impact on me in terms of male aspects. If the prostate cannot excrete, will it affect androgens, and so on? I am a bit worried. Please help all the doctors. Thank you.

Doctor's answer:

The main component of Indomethacin patches is a prostaglandin synthesis inhibitor, but it cannot be assumed from the name alone that it is a drug affecting the prostate. Experiments have also shown that prostaglandins are not produced by the prostate but are instead a hormone secreted and excreted by the seminal vesicles. Many parts of the body can also arachidonic acid into prostaglandins. Therefore, based on your symptoms, using this medication is very appropriate. Local application will only have a therapeutic effect and will not cause other serious discomforts. You only need to pay attention to whether there is a recurrence of allergy at the application site. Only in this way can you enhance the patient's confidence in combating the prostate and believe that recovery can definitely be achieved.

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