What is the effect of chlorpromazine on male sexual function?

Patient's question:

After taking the medication for 3 months, erectile difficulties have started to reappear. Occasionally, the duration and hardness of erections have significantly declined (similar to premature ejaculation). What are the effects of chlorpromazine on male sexual function?

Doctor's answer:

Chlorpromazine and other antipsychotic drugs can cause sexual dysfunction, with decreased libido being the most common; it is a normal reaction to the medication. Chlorpromazine is a central dopamine receptor antagonist. When taken by psychiatric patients, it often causes symptoms such as nausea, abdominal pain, blurred vision, abnormal penile erection, difficulty achieving erection, weak ejaculation, sexual apathy, and incontinence without excessive suppression. Taking Wuzi Yanzong Wan orally can help regulate the body and tonify the kidneys and essence. It is used to treat kidney deficiency lower back pain, post-micturition dribbling, premature ejaculation, and infertility due to premature ejaculation. Rest, drink plenty of water, and maintain a light diet.

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