What are the causes of epididymal malformation?

Patient's question:

I don't have any bad habits, and I look quite healthy. I've been married to my wife for several years and have been trying to get pregnant, but for some reason, it just hasn't worked. Also, I have a little cyst in my epididymis, but I don't have any other symptoms. They say infertility is caused by epididymal malformation. What should I do?

Doctor's answer:

The etiology of epididymal malformation is still unclear. Since patients with cryptorchidism often have epididymal malformation, its recurrence may be related to endocrine dysfunction during embryonic growth and development. Due to excessively high testosterone levels, the mesonephric tubules and mesonephric ducts fail to develop or develop incompletely, resulting in various types of epididymal malformation. If the mesonephric ducts fail to develop at all, it can lead to congenital absence of the epididymis and vas deferens. Timely treatment can reduce the incidence, so patients should seek appropriate medical treatment promptly and avoid overexertion in daily life while paying attention to personal hygiene.

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